
A rare, severe form of pulmonary hypertension, which up until now, has
only been classified as a human lung disease, has also been discovered
in dogs according to a Michigan State University study.
"Our research is the first to document the existence of pulmonary veno-occlusive disease, or PVOD, in
dogs," said Kurt Williams, the lead author of the
study and an expert in respiratory pathology in MSU's College of
Veterinary Medicine. "PVOD is considered one of the most severe forms of
pulmonary hypertension."
The study is published in the journal Veterinary Pathology.
The number of pulmonary hypertension, or PH, cases reported in the
United States is low, affecting 15 to 50 people per million each year.
PVOD is diagnosed in only about 10 percent of PH cases where no other
cause of the disease has been determined. Unfortunately, there are very
few effective treatment options for PVOD and a lung transplant often
becomes the best choice.
"PVOD might be more common in dogs than in people, but this has yet to
be determined and needs to be looked at further," Williams said.
Pulmonary hypertension develops because of abnormal blood vessels in the
lungs, which makes it harder for the heart to push blood through and
provide oxygen to the rest of the body. In cases of PVOD, the small
veins in the lungs become blocked, increasing pressure in these blood
vessels, and ultimately causing heart failure.

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